Due

to time constraints data was only buy Cobimetinib collected for one day at two different hospital anticoagulant clinics (A and B) and analysed with particular importance on the non-attendance for the ‘AMA’ and dosage change. The data was collected in person in pre-populated tables by recording the number of patients booked to the clinic in question and then tallying the number of patients who attended the clinic and also the number of patients who had a dose change during their appointment. This date was then retrospectively compared to attendance to ‘AMA’ at Clinic B over the past 20 months and also against the national average for any missed outpatient appointment. Statistical analysis was carried on the data for correlation of missed appointments Pifithrin-�� in different

months at Clinic B and significance of the results between the two clinics. Ethics approval was not required. Table 1 The results obtained from Clinics A and B during data collection Anticoagulant clinic A B Total patients booked on the specific clinic day 45 56 Patients who did not attend (DNA) 7 12 % DNA for this clinic 15.55% 21.43% % Patients who had a dose change 72.5% 46.8% The results obtained from clinics A and B show that at both clinics that a larger percentage of patients did not attend their ‘AMA’ (18.49% average) compared to the national average of 7.7% of patients who did not attend general NHS outpatient appointments. In comparison C59 cost the retrospective results shown in Figure 1, gave a lower average non-attendance rate of 11.53% at Clinic B over the past 20 months for ‘AMA’. This value maybe more accurate due to larger sample of data, however this is still 3.83% higher than the national average and therefore is a major cause for concern in regards to patient safety. Patients who miss their appointments ultimately would still continue to take their medication at the old dose and therefore putting themselves at high risk of adverse effects such as uncontrollable bleeding or an increased of stroke if their INR is out or range. The results obtained from clinics A and B also show that a large and significant percentage

of patients had their dose amended during their appointments (72.5% at clinic A and 46.8% and clinic B) and therefore the particular importance in therapeutic monitoring to ensure patients have a better control of their individual INR levels. In relation to these findings the current anticoagulant clinic monitoring system has various flaws, mainly linked to the poor communication between primary and secondary care to ensure patients have had their INR monitored regularly. A novel electronic Warfarin Yellow card system could be introduced to increase the communication between these care sectors and would allow for information to be easily transferred and allow a safer and more transparent share of care. H. Stokesa, J.