Once an ovarian origin was confirmed, total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed for definitive treatment. The adrenal adenoma was left in situ. There was a dramatic decrease Cell Cycle inhibitor in subjective symptomatology and normalization of testosterone postoperatively.
CONCLUSION: Preoperative differential venous sampling determined the correct source of testosterone. Subsequent removal of the ovary and steroid cell tumor correctly treated the hyperandrogenism and avoided an unnecessary surgical procedure for the adrenal adenoma. (Obstet Gynecol 2012;120:476-9) DOI: 10.1097/AOG.0b013e31825a711c”
“The ankle-brachial index (ABI) is used
in the screening diagnosis of peripheral artery disease (PAD). Lower limb ischemia is diagnosed selleck chemicals if ABIa parts per thousand currency sign0.9. However, persons with ABI > 1.4 also suffer from leg ischemia. Not taking this into consideration may lead to diagnostic mistakes and an underestimation of cardiovascular risk.
This study addresses the analysis of clinical conditions related to an elevated ABI.
One hundred and twenty-two randomly chosen subjects over 50 were treated in internal medicine ward were studied using questionnaire and ABI determination.
Forty-four (34%) patients had elevated ABI > 1.4 and in 23 (19%) subjects ABI wasa parts per thousand currency sign0.9. Patients with ABI > 1.4,
in comparison to individuals with 0.9 < ABIa parts per thousand currency sign 1.4, presented significantly greater BMI, more atherosclerosis risk factors, more prevalent past stroke and angina pectoris. In comparison to patients with ABIa parts per thousand currency sign0.9, they showed higher blood pressure and lower LDL cholesterol concentration. In the
diagnosis of ABI > 1.4, lack of palpable pulse in at least one lower limb artery had CUDC-907 cell line a sensitivity of 6.8%, specificity of 91%, PPV of 30%, NPV of 63.4%, a likelihood ratio positive 0.75 and for negative 1.02; pulse pressure above 55mmHg had similar low diagnostic yield, respectively: 36.4%, 71.8%, 42.1%, 66.7%, 1.29 and 0.89. In logistic regression only LDL value was a significant predictive factor for elevated ABI, but with a very low odds ratio value for separate increments.
In the diagnosis of lower limb ischemia and connected cardiovascular risk, ABI determination should be obligatory, besides atherosclerosis risk factors, peripheral pulse and pulse amplitude determination.”
Injury is a common initiating event for persistent pain. The presentation of injured patients to hospital represents an opportunity to identify patients at high risk of persistent pain and triage them to early intervention. Although a range of physical, psychological, and social risk factors have been implicated in the transition from acute to persistent pain, these factors have not been tested concurrently in a prospective study.