03] and ‘number of HIV/AIDS patients’ (IRR = 1 30; 95% CI 1 02-1

03] and ‘number of HIV/AIDS patients’ (IRR = 1.30; 95% CI 1.02-1.66; P < 0.001).

Conclusions Since 1991, there has been increasing epidemiological research productivity in

WHO/AFRO that is associated with the number of epidemiology programmes and burden of HIV/AIDS cases. More capacity Selleck SNX-5422 building and training initiatives in epidemiology are required to promote research and address the public health challenges facing the continent.”
“OBJECTIVE: To compare the effectiveness of two second-generation ablation techniques, bipolar radiofrequency impedance-controlled endometrial ablation and hydrothermablation, in the treatment of menorrhagia.

METHODS: This study was a double-blind, randomized controlled trial, which took place in a large teaching hospital in The Netherlands with 500 beds. Women with menorrhagia were randomly Bcl-2 inhibitor allocated to bipolar radiofrequency ablation (bipolar group) and hydrothermablation (hydrotherm group). At follow-up, both women and observers remained unaware of the type of treatment that had been performed. The primary outcome was amenorrhea. Secondary outcome measures

were patient satisfaction and reintervention.

RESULTS: We included 160 women in the study, of which 82 were allocated to the bipolar group and 78 to the hydrotherm group. No complications occurred in either of the treatment groups. After 12 months, 87% (65 of 75) of the patients in the bipolar group were completely satisfied with the result of the treatment compared with 68% (48 of 71) in the hydrotherm group (relative risk 1.3, 95% confidence interval [CI] 1.03-1.6). The amenorrhea rates were 47% (35 of 75) in the bipolar group and 24% (17 of 71) in the hydrotherm group (relative risk 2.0, 95% CI 1.2-3.1). The relative risks for a reintervention in the bipolar group compared with the hydrotherm group was 0.29 (95% CI 0.12-0.67), whereas for hysterectomy, this was 0.49 (95% CI 0.15-1.5).

CONCLUSION: In the treatment of menorrhagia,

bipolar radiofrequency endometrial ablation system is superior to hydrothermablation. (Obstet Gynecol 2010;116:819-26)”
“Background: Accurate interpretations DMH1 clinical trial of cardiac functions require precise structural models of the myocardium, but the latter is not available always and for all species. Although scaling or substitution of myocardial fiber information from alternate species has been used in cardiac functional modeling, the validity of such practice has not been tested.

Methods: Fixed mouse (n = 10), rabbit (n = 6), and sheep (n = 5) hearts underwent diffusion tensor imaging (DTI). The myocardial structures in terms of the left ventricular fiber orientation helix angle index were quantitatively compared between the mouse rabbit and sheep hearts.

Results: The results show that significant fiber structural differences exist between any two of the three species.

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