Curr Opin Genet Dev 1998, 8:423–429.PubMedCrossRef 16. Moens CB, Selleri L: Hox cofactors in vertebrate development. Dev Biol 2006, 291:193–206.PubMedCrossRef 17. Chung EY, Liu J, Homma Y, Zhang Y, Brendolan A, Saggese M, Han J, Silverstein R, Selleri L, Ma X: Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1. Immunity 2007, 27:952–964.PubMedCrossRef 18. Deflorian G, Tiso N, Ferretti E, Meyer D, Blasi F, Bortolussi M, Argenton F: Prep1.1 has essential genetic functions in hindbrain development and cranial neural crest cell differentiation.
Development 2004, 131:613–627.PubMedCrossRef 19. Penkov D, Di Rosa P, Fernandez Diaz L, Basso V, Ferretti E, Grassi F, Mondino A, Blasi F: Involvement of Prep1 in the alphabeta T-cell receptor T-lymphocytic potential of hematopoietic selleck screening library precursors. Mol Cell Biol 2005, mTOR inhibitor 25:10768–10781.PubMedCrossRef 20. Ferretti E, Villaescusa JC, Di Rosa P, Fernandez-Diaz LC, Longobardi E, Mazzieri R, Miccio A, Micali N, Selleri L, Ferrari G, Blasi F: Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic selleck compound phenotype. Mol Cell Biol 2006, 26:5650–5662.PubMedCrossRef 21. Roschke AV, Tonon G, Gehlhaus KS, McTyre N, Bussey KJ, Lababidi S, Scudiero DA, Weinstein JN, Kirsch IR: Karyotypic complexity of the NCI-60 drug-screening panel. Cancer Res 2003, 63:8634–8647.PubMed 22.
Micali N, Ferrai C, Fernandez-Diaz LC, Blasi F, Crippa MP: Prep1 directly regulates the intrinsic apoptotic pathway by controlling Bcl-XL levels. Mol Cell Biol 2009, 29:1143–1151.PubMedCrossRef 23. Allen TD, Zhu YX, Hawley TS, Hawley RG: TALE homeoproteins as HOX11-interacting partners in T-cell leukemia. Leuk Lymphoma 2000, 39:241–256.PubMedCrossRef 24. Kumar AR, Li Q, Hudson WA, Chen W, Sam T, Yao Q, Lund EA, Wu B, Kowal BJ, Kersey JH: A role for MEIS1 in MLL-fusion gene leukemia. Blood 2009, 113:1756–1758.PubMedCrossRef 25. Geerts
D, Schilderink N, Jorritsma G, Versteeg R: The role of the MEIS homeobox genes in neuroblastoma. Cancer Lett 2003, 197:87–92.PubMedCrossRef 26. Kawagoe H, Humphries RK, Blair A, Sutherland HJ, Hogge DE: Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells. Ketotifen Leukemia 1999, 13:687–698.PubMedCrossRef 27. Argiropoulos B, Yung E, Humphries RK: Unraveling the crucial roles of Meis1 in leukemogenesis and normal hematopoiesis. Genes Dev 2007, 21:2845–2849.PubMedCrossRef 28. Wermuth PJ, Buchberg AM: Meis1-mediated apoptosis is caspase dependent and can be suppressed by coexpression of HoxA9 in murine and human cell lines. Blood 2005, 105:1222–1230.PubMedCrossRef 29. Fujino T, Yamazaki Y, Largaespada DA, Jenkins NA, Copeland NG, Hirokawa K, Nakamura T: Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes. Exp Hematol 2001, 29:856–863.PubMedCrossRef 30.