Demographic characteristics, body mass index (BMI) and condition of fatty liver were retrospectively reviewed. The prognosis of patients was compared between the fatty liver and the non fatty liver group. Results: Fatty liver was diagnosed in 29.17% (35/120) of our patients. Fatty liver correlated with higher incidence of SAP (62.9% vs. 29.4%, p = 0.001), systemic inflammatory response syndrome (SIRS) (57.1% vs. 37.6%, p = 0.050), pulmonary failure (45.7% vs. 20.0%,

p = 0.004), severe metabolic disturbance (37.1% vs. 12.9%, p = 0.003), higher level of APACHE-II score (p = 0.007) and SIRS score Selleck SCH772984 (p = 0.009). Higher level of BMI was also detected in patients with fatty liver (p < 0.001). Multiple analysis demonstrated that only fatty liver independently correlated with SAP (OR 3.95, 95%CI 1.43–10.93), systemic complications

(OR 4.22, 95%CI 1.49–11.95) and pulmonary failure (OR 4.02, 95%CI 1.38–11.73). Conclusion: Fatty liver is an independent risk factor for SAP and systemic complications of AP. It is probable that fatty liver correlates more closely with the severity of AP than obesity. Key Word(s): 1. acute pancreatitis; 2. fatty liver; 3. prognosis; Table 2. Logistic analysis for obesity and fatty liver in the prognosis of AP   p OR 95% CI Age, sex, and etiology were also entered into the logistic analysis but were not found to be relevant to the incidence of SAP, systemic complication or pulmonary failure. Presenting Author: GUOYING WANG Additional Authors: JIAN ZHANG, GUI-HUA CHEN Corresponding Author: GUOYING WANG Affiliations: GSK2126458 Liver Transplantation Center, the third affiliated hospital of sun yat-sen university Objective: Alpha-fetoprotein (AFP) has been proposed to correlate with vascular invasion of hepatocellular carcinoma (HCC) and predict tumor recurrence after liver transplantation (LT). However, the prognostic value of AFP in patients with HCC without vascular invasion during the waiting list for LT has not been clearly defined. In this study, we determined the prognostic role of preoperative AFP in patients who underwent LT for HBV-associated HCC

without vascular invasion. Methods: We analyzed the outcome of 80 patients who underwent LT for HBV-associated HCC without vascular invasion. Vascular invasion was defined as the presence of tumor emboli within the lobar or segmental branches of the portal or hepatic others veins, which was diagnosed or highly suspected by preoperative imaging examination. Patients were divided into two groups according to different AFP cut-off level (20 ng/mL, 100 ng/mL, 200 ng/mL, and 400 ng/mL). Results: The 1-, 3- and 5-year disease-free and overall survivals were 97.1%, 89.1%, and 79.9%, and 92.1%, 81.5%, and 72.7%, respectively. Ten patients developed tumor recurrence and 13 patients died during 6 years of follow-up. Univariate analysis revealed that multiple tumor number was the only preoperative predictor of disease-free survival (DFS).