Local mass is the main symptom, the main pathology is epithelial type, elevated platelets Deforolimus solubility dmso and CA125 are the characteristics of peritoneal mesothelioma. Key Word(s): 1. peritoneal; 2. mesothelioma; 3. localized; 4. asbestos; Presenting Author: ZHU JIN

Additional Authors: HEJUN ZHANG, RONGLI CUI, YAJING HAN, YING ZHANG, HUIRU SHANG Corresponding Author: ZHU JIN Affiliations: Peking University Third Hospital Objective: To investigate the pathological features of early adenocarcinoma in the distal esophagus and proximal stomach. Methods: To analyse retrospectively the clinical data of early adenocarcinoma arised within the distal/proximal 3 cm of the gastroesophageal

junction (GEJ), including endoscopic appearance, post-operative pathological results, from January 2011 to February 2013. Results: There were 26 early adenocarcinoma cases. The mean age was 64.2 ± 8.3 yrs (range 46–82 yrs), and the ratio of male to female was 20 : 6. The vast majority of cases (96.2%, 25/26) localized on distal GEJ (i.e. proximal stomach), and the other case localized on GEJ. Under endoscopy, the macroscopic appearance of the early adenocarcinoma of the oseophago-gastric junction area included type I (Figure 2) APO866 and type II. Type II accounted for 88.5% (23/26), and type IIc (47.8%, 11/23) (Figure 1) and type IIb (34.8%, 8/23) were the most common subtype, the other subtype including type IIa, type IIa+IIc, represented 4.3% and 13.0%, respectively. Histopathologically, the majority of early adenocarcinoma were tubular adenocarcinoma (Figure 1), occupied 80.8% (21/26). The tubular adenocarcinoma with papillary adenocarcinoma, tubular adenocarcinoma with signet ring carcinoma (Figure 2), and poorly differentiated adenocarcinoma

represented 7.7% (2/26), 7.7% (2/26), and 3.8% (1/26) of cases, respectively. Conclusion: The early adenocarcinoma of the oseophago-gastric junction area was most commonly found in 上海皓元 distal GEJ (proximal stomach), type IIc and type IIb were the most common subtype. Histopathologically, tubular adenocarcinoma was common. Key Word(s): 1. adenocarcinoma; 2. Osephagogastric; 3. Pathology; Presenting Author: SIJUN HU Additional Authors: JUN TIE, YONGZHAN NIE, DAIMING FAN, KAICHUN WU Corresponding Author: SIJUN HU Affiliations: Xijing Hospital of Digestive Diseases & State Key Laboratory of Cancer Biology, Fourth Military Medical University, Objective: MicroRNAs (miRNAs) play important roles in gastric cancer (GC) metastasis. More information on metastamirs will promote a better understanding of the molecular mechanism of GC metastasis.