Sample The inclusion criteria for this study were that the subjects needed selleckchem to be 18 years of age or older on the date of being approached regarding the interview, needed to be living in the home of the family that was drawn, could not be practicing any form of leisure-time physical activity during the month preceding the interview and could not Inhibitors,Modulators,Libraries be practicing physical activity for transportation (walking or cycling) of duration greater than or equal to 150 minutes in the week preceding the interview.

The exclusion criteria were as follows: a) type 2 diabetes; b) severe arterial Inhibitors,Modulators,Libraries hypertension or using beta-blockers for treating hypertension or cardiovascular disease; c) a health problem or disease that would Inhibitors,Modulators,Libraries make the individual incapable of leaving home and making the journey to practice physical activity at the time of the interview; d) diseases at advanced stages, such as cancer, cirrhosis, chronic kidney disease, Chagas disease, chronic obstructive pulmonary disease, chronic bronchitis, osteoporosis or severe depression (information gathered by questionnaires); e) a cognitive problem or disease that would prevent the individual from answering the questionnaire alone; f) morbidly obese, with a body mass index (BMI) greater than or equal to 40 kg.m-2; g) plans to move house over the two-year period subsequent to the date of being approached; and h) pregnancy. It was defined that all members of the family drawn who were not covered by any of the exclusion criteria would be invited to participate in the study.

According to published data, Inhibitors,Modulators,Libraries the adhesion to interventions (subjects who received the invitation and agreed to participate) was 63% [26]. Therefore, the challenge of both interventions was to stimulate a more active lifestyle for individuals who are not initially engaged in leisure-time Inhibitors,Modulators,Libraries physical activity, without any kind of chronic disease, and not considering becoming physically active as a priority. To calculate the sample size, Brefeldin_A results from previous representative population-based surveys among adults living in Ermelino Matarazzo were used [27]. For adults living in Ermelino Matarazzo who were not active in transportation, the mean time of leisure-time physical activity was 68.1 minutes per week (standard deviation=146.1 minutes.week-1) [28]. For the individuals targeted in this intervention study (adults who were physically inactive during leisure time and insufficiently active in transportation), the goal was to reach a mean 150 minutes of leisure-time or commuting physical activity per week. The goal of stimulating the practice of 150 minutes of physical activity during leisure time or commuting is in agreement with Brazilian studies published previously [29,30].