The study after single oral administration of Hypericum perforatum and Rosmarinus officinalis extracts revealed a statistically significant reduction in immobility time in FST, RRT, and protection against HIC, compared to control respectively. However, there was no significant potentiation of PST. The results of our study demonstrate the extracts of Hypericum perforatum and Rosmarinus officinalis proved to have a promising antidepressant potential.”
“Objective: To demonstrate a case series of granulocytic
sarcoma of the head and neck found in the pediatric population and review long-term outcomes.
Methods: A pathology database at a Vorinostat tertiary hospital was searched for patients with biopsy specimens from the head and neck diagnosed as granulocytic sarcoma.
Results: There were 6 cases between 1992 and 2004 that met inclusion criteria. Subjects’ age ranged from 22 months to 14 years old. In three cases, the patients were diagnosed with acute myeloid leukemia (AML) based on biopsy results; 2 patients were already diagnosed with AML when diagnosed with granulocytic sarcoma, and in 1 case, a relapse of AML was diagnosed. In all cases, patients began induction chemotherapy. Two patients died during induction chemotherapy from infection. The remaining 4 patients underwent bone marrow transplants. One patient had a relapse post-transplant and died.
AL3818 in vivo Only one patient was healthy two years post-transplant.
Conclusion: The results of this series suggest granulocytic sarcoma must be on the differential when tumors present in the head and neck region in this website pediatric patients. In our series, 100% of the patients with granulocytic sarcoma had underlying AML. The long-term prognosis of patients with AML who developed granulocytic sarcoma is quite poor. (C) 2013 Elsevier Ireland Ltd. All rights reserved.”
“Polymeric membranes have been used as wound dressings for burns and healing wounds. Healing properties,
anti-inflammatory and antibiotic in such membranes can be induced and/or made possible with the incorporation of bioactive as phytotherapic extract. In this work chitosan membranes were produced incorporating a commercial phytotherapic extract. The membranes were prepared by casting a chitosan solution and phytotherapic extract in a Petri dish and dried for 24 hs. We studied the effect of the concentration of the phytotherapic extract (PE) on membranes properties. Additionally, membranes were prepared with silver sulfadiazine (SS), an antibiotic ointment used for burns. The membranes were characterized for thickness, water vapor permeability rate, water uptake capacity, erosion degree and infrared spectroscopy. The results showed that the incorporation of low Concentrations of extract promotes changes in the water uptake capacity and erosion degree, while high concentrations promote changes in the water vapor permeability.