Br J Cancer 2004, 91:355–358 PubMed 26 Shigematsu H, Takahashi T

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of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature 2007, 448:595–599.PubMedCrossRef 30. Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, Varambally S, Cao X, Tchinda J, Kuefer R: Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005, 310:644–648.PubMedCrossRef 31. Raz DJ, He B, Rosell R, Jablons DM: Current concepts in bronchioloalveolar carcinoma biology. Clin Cancer Res 2006, 12:3698–3704.PubMedCrossRef Competing interest The authors declare that they have no competing interests. Authors’ contributions MLM carried out the RNA extraction, primer design and PCR. TH carried out the DNA extraction and sequencing analysis. ZC and HL performed the statistical analysis. DJ participated in the design of the study. HMZ and BH conceived of the study, and participated in its design and coordination and helped to draft the manuscript. All authors read and approved the final manuscript.”
“Introduction Wrist fracture or distal forearm fracture is one of the major osteoporotic fractures [1]. It causes Cyclin-dependent kinase 3 pain

and acute loss of physical function and has an impact on social and emotional function [2, 3]. Algodystrophy or complex regional pain syndrome is a debilitating consequence occurring in between 1% and 20 % of see more patients with distal forearm fracture [4]. Wrist fracture occurs early in the course of osteoporosis, and many patients are still employed. The socioeconomic impact of this fracture therefore is considerable. A wrist fracture often is a predictor of other fractures. Osteoporotic fractures, such as vertebral and hip fractures, cause a considerable loss of quality of life, both acute loss, immediately after the fracture, and chronic loss because of recurrent fractures and disability due to incomplete recovery [5–9]. Several instruments have been developed for the assessment of quality of life after vertebral fractures.

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