(C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci 123: 1100-1111, 2012″
“Time evolution of the discharge plasma in the dielectric barrier discharge (DBD) plasma actuator was simulated by the simple fluid model in which the electron and single positive ion species were considered. Selleck OICR-9429 The characteristics
of the discharge plasma evolution were investigated in detail, and the following results were obtained. When the positive-going voltage is applied, the streamer discharge is formed periodically. The periodically formed streamer expands from the exposed electrode, and its length becomes longer than the previous one. Periodic breakdown of the gas and step-by-step plasma expansion are also observed during the negative-going voltage; however, the streamer is not formed and the breakdown frequency is much higher. The simulation results with a triangular applied voltage waveform show the same characteristics as observed in the experiment; large discharge current spikes are observed during both the positive- and negative-going voltage phase, and the plasma in
the negative-going voltage phase PFTα expands more smoothly than that in the positive phase because of its higher breakdown frequency. It was shown that even the simple numerical model could provide valuable insights into the physics of DBD plasma actuator; this indicates that the positive ions and electrons play a prominent role in determining the general characteristics of the plasma evolution. (C) 2011 American Institute of Physics. [doi:10.1063/1.3603001]“
“In murine models, the adoptive transfer of CD4+/CD25+ regulatory T cells (T(regs)) inhibited graft-versus-host disease (GvHD). Previous work has indicated a critical role for the adhesion molecule L-selectin (CD62L) in the function of T(regs) in preventing GvHD. Here we examined the capacity of naive wild-type (WT), CD62L-/- and ex vivo expanded CD62LLo T(regs) to inhibit Q VD Oph acute GvHD. Surprisingly, we found that CD62L-/- T(regs) were potent suppressors of GvHD, whereas CD62LLo T(regs) were unable to inhibit disease despite being functionally competent to suppress allo T cell responses in vitro.
Concomitant with improved outcomes, WT and CD62L-/- T(regs) significantly reduced liver pathology and systemic pro-inflammatory cytokine production, although CD62L-/- T(regs) were less effective in reducing lung pathology. While accumulation of CD62L-/- T(regs) in GvHD target organs was equivalent to WT T(regs), CD62L-/- T(regs) did not migrate as well as WT T(regs) to peripheral lymph nodes (PLNs) over the first 2 weeks posttransplantation. This work demonstrated that CD62L was dispensable for T(reg)-mediated protection from GvHD.”
“Mesh-like fiber mats of polystyrene (PS) were deposited using DC-biased AC-electrospinning. Superhydrophobic surfaces with water contact angles greater than 150 degrees and gas fraction values of up to 97% were obtained.